Human rhinoviruses group of viruses — of which there are more than 100 types — is by far the most common identified cause of colds. The viruses grow best at the temperature inside the human nose.
Human rhinoviruses (HRVs) are highly contagious. However, they rarely lead to serious health consequences.
Recent research has found that HRVs manipulate genes and it is this manipulation that brings about an overblown immune response. The response causes some of the most troublesome cold symptoms. This information could lead scientists to important breakthroughs in the treatment of the common cold.
Potential complications of infection include otitis media, sinusitis, chronic bronchitis, and exacerbations of reactive airway disease (eg, asthma). Although rhinovirus infections occur year-round, the incidence is highest in the fall and the spring.
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